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The peptide inhibits nuclear factor-B (NF-B) activation, a master regulator of inflammatory gene expression, while simultaneously activating peroxisome proliferator-activated receptor- (PPAR-), which promotes inflammatory resolution

Combination likely superior to either alone addressing both immediate oxidative stress and enhancing cellular defenses

Rapid and general profiling of protease specificity by using combinatorial fluorogenic substrate libraries

Non-viral LNP-mediated delivery of 5moU-modified ABE mRNA and guide RNA successfully corrected the Fah point mutation in the hepatocytes of mice with tyrosinemia I