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Cinnamaldehyde and its combination with deferoxamine ameliorate inflammation, ferroptosis and hematoma expansion after intracerebral hemorrhage in mice

Jin L, Zheng D, Mo D, Guan Y, Wen J, Zhang X, et al

John's Hospital, Vienna, Austria, Vienna, Austria, 5 Department of Neurology, Helsinki University Hospital and University of Helsinki, Finland, Helsinki, Finland, 6 Department of Neurology & Stroke, University of Tbingen, Tbingen, Germany, Tubingen, Germany, 7 Department of Diagnostic and Interventional Neuroradiology, University of Tbingen, Tbingen, Germany, Tubingen, Germany, 8 Department of Diagnostic and Therapeutic Neuroradiology, CHRU Nancy, Nancy, France Background and Aims: Whether intravenous thrombolysis (IVT) should be administered in eligible patients before endovascular treatment(EVT) in patients with acute vertebrobasilar occlusion remains an open question

L-Arg and the cofactors H 4 B and Zn play a central role in NOS coupling, with their deficiency resulting in the enzyme generating the free radical O 2 - as a replacement of NO [3] (Table 1a)