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The mechanisms underlying this activity include a reduction in purine/pyrimidine synthesis and genomic and/or specific methylation reactions in brain, leading to decreased DNA stability and altered gene expression resulting in the mental dysfunction [22]

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Regarding the in vitro comet assay response, NFluo was thus ranked higher than NDMA followed by NMtBu with a relatively higher BMD 100 CI ratio of 20

A variety of analytical techniques, such as chromatography, mass spectrometry (MS), electrochemical methods, spectrophotometry, fluorescence methods, and radioenzymatic assays (REAs), have been developed for carnitine detection