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Similarly, if Cu 2+ weakly bound to the sulfur atom of Met35 is the recipient of an electron from this S-atom to form the reduced Cu + (see above for discussion of a relatively weaker electron pair interaction with the S-atom protons in a polypeptide with -helical structure), this latter moiety can lead to the highly reactive hydroxyl free radical by Fenton chemistry as noted, initiating lipid peroxidation

Stable pH was found to be pH = 8.5 in Tris/HCl buffer

Mangiferin in a murine neuroblastoma cell line (N2A) at a concentration of 0.25 mM protects against oxidative stress-induced toxicity caused by 1-methyl-4-phenylpyridinium

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