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2008;26:2725 Schmidt C, Sciacovelli M, Frezza C

During the normal cell cycle, any cell which becomes damaged or old dies and is replaced by a newly generated cell

A planned sample size of 190 subjects with complete observations yielded 80% power at the 5% two-sided significance level to detect a difference in the primary endpoint (hospitalization) rate of 10% in the resveratrol arm versus 25% in the placebo arm