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Based on advanced physiological studies, some new targets could be tested

Indian J Med Microbiol 37:511

Moreover, nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha (IB) phosphorylation, nuclear translocation of p65, p50, and p105 NF-B subunits, and NF-B DNA-binding transcriptional activity were suppressed by XN treatment of DSS-treated mice and H 2 O 2 - or LPS-treated IEC-6 cells (101)