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No significant changes were observed in Mobility, Emotional Well-being, Stigma, and Communication

To advance research in this area, investigators have been documenting complications associated with immunotherapy drugs, studying the biological mechanisms, modifying immunotherapy drugs to reduce their side effects, and increasing awareness of potential side effects among clinicians and patients

PLoS ONE 9 , e84369 (2014)

In contrast, PINK1-PARKIN independent mitophagy relies on mitophagy receptors, mitochondrial membrane proteins (e.g., BNIP3, BNIP3L/NIX, FKBP8, FUNDC1), which can interact with LC3 or GABARAP proteins to recruit dysfunctional mitochondria to autophagosomes