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Description

Selective covalent targeting of GPX4 using masked nitrile-oxide electrophiles

The administration of glutamine regulates protein expression through mitochondrial oxidative phosphorylation pathways, specifically the essential subunits of NADH and the glutathione (antioxidant-forming) system

doi: 10.1136/thoraxjnl-2017-211090 57 KojicicMLiGHansonACLeeKMThakurLVedreJet al

The capability to reversibly change signals in response to varying concentration environments allows for the effective differentiation of biomarker concentration levels between tumor tissues and normal tissues (Supplementary Fig