Mal-Propionyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG4) propargyl-acetyl while the para-aminobenzyl (PAB) spacer

while the para-aminobenzyl (PAB) spacer supports self-immolative release of the attached drug

HQ461 is a molecular glue that promotes CDK12-DDB1 interaction to trigger cyclin K degradation

Product Name: Cy3 azide trisulfo Synonyms: Cy3 azide

Product Name Lenalidomide-PEG5-propargyl Synonyms Lenalidomide-4'-PEG5-propargyl CAS Number n/a Related CAS Molecular Formula C26H35N3O8 Molecular Weight 517

Mal-Propionyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG4) propargyl-acetyl while the para-aminobenzyl (PAB) spacerSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Propionyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. Additionally, m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. Derived from