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This key role of antioxidants on microbiota probably extends beyond the digestive tract, as the beneficial effect of butyrate has been suggested for other human microbial ecosystems, such as the skin 46 , the gut-brain axis 47 and atopic diseases 48

Supplementary material The Supplementary Material for this article can be found online at: Abbreviations AUC, area under the curve

elegans does not encode PRX4, but PRX1/2 that lacks 3 residues)