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According to his obit in the LA Times, Arness, who prior to 'Gunsmoke' had appeared in a number of movies, was reluctant to take the part of Dillon, fearing it would hinder his big-screen career

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By reducing the availability of these products and imposing tough penalties, the government hopes not only to discourage vaping, but also to send a clear message about its commitment to preventing health risks associated with non-medical nicotine use

Importantly, the current study was designed to detect a difference between randomised groups and so these factors should not cause a bias of the effect estimate as these factors will not affect the separate groups differentially