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Untangling the potential effects of these diuretics on fuel homeostasis is additionally complicated by the intricate relationships among all components of the MetS, glucose intolerance (often confused with prediabetes), T2D, hypertension, the specific diuretic treatment and the functional redundancy that may exist among diuretic-sensitive targets

The most frequently occurring adverse reactions (at least 1%) in all three groups were headache (5.5%, 5%, and 3.8%, respectively) and diarrhea (no difference among the three groups)

The sample presented 30.5% of non-psychiatric comorbidities