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We then pre-incubated early ring-stage artemisinin resistant and sensitive parasites with BSO for 1 h prior to pulse treatment with 700 nM of DHA for 6 h and measured survival, analogous to the standard in vitro Ring-stage Survival Assay (RSA) for artemisinin resistance

The non-provitamin A carotenoid, lutein, inhibits NF-kappaB-dependent gene expression through redox-based regulation of the phosphatidylinositol 3-kinase/PTEN/akt and NF-kappaB-inducing kinase pathways: Role of H(2)O(2) in NF-kappaB activation

S7D-F, S8-10).Of note: TDP-43 K408R/+ mice are generally omitted from figures for clarity to avoid confounding variables that may arise due to asymmetric regulation of wild type and K408R alleles due to the autoregulatory nature of TDP-43 (i.e

[DOI] [PubMed] [Google Scholar] 17.Pickart L, Vasquez-Soltero JM, Margolina A