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Med Phys 32(6):2144, 2005

37, 16981714.e5

doi: 10.1016/0887-2333(94)00187-Y

They found that the knockdown of endogenous IRS-1 significantly decreased PI3K/AKT signaling and this effect was similarly shown in BC cells with miR-148a or miR-152 overexpression leading to the inhibition of cell proliferation