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78 In fact, the authors of a review that mentioned this study noted it was not overly informative and reliable due to those limitations

Arch Biochem Biophys 319:128132 Hasan NM, Longacre MJ, Stoker SW et al (2008) Impaired anaplerosis and insulin secretion in insulinoma cells caused by small interfering RNA-mediated suppression of pyruvate carboxylase