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doi: 10.1016/j.ypmed.2012.01.003 33 TylerJBolisSDingleJTMiddletonJFS

found that non-mitochondria-targeting antioxidants, such as NAC and Trolox, prevented hepatic tumorigenesis, whereas mitochondria-targeting antioxidants, such as SS-31 and Mito-Q, accelerated HCC (Wang B

The first reported cardiovascular complication of anticancer drugs was a decrease in the left ventricular ejection fraction, leading to heart failure (HF) in patients treated with anthracyclines 3