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Description

10.1016/j.cell.2005.09.028 Cell 122 StefanieP.KenA.XiaoyingW.LoE

SILY: Silymarin

This leads to enhanced protection against viruses, infections, and antigens

By favoring conversion of RAS from its active state to its inactive state, neurofibromin downregulates the downstream effects of RAS, which include promoting learning, memory, synaptic plasticity, and cell growth and proliferation.4,6 Mediators of the downstream effects of RAS include mitogen-activated protein kinase (MAPK), phosphatidylinositol 3-kinase (PI3K), protein kinase B (PKB), and mammalian target of rapamycin (mTOR) kinase