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Here are the most cited benefits: Increased procollagen synthesis: Abdulghani et al

The mechanisms appear to involve enhanced blood flow, antioxidant effects, and support of hepatocyte regeneration

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With physician-compounded topical formulations used daily, patients consistently report improved skin texture and smoothness at weeks 2 to 4, increased firmness and reduced fine line visibility at weeks 6 to 10, better hydration and radiance that holds with continued use, and a gradual improvement in skin tone evenness over 3 to 6 months