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The latter can be reduced by thioredoxin (Trx) 2, which is further reduced by thioredoxin reductase [28]

The major limitations of these studies included were small sample size consisting of healthy Volunteers, extremely short study periods with an even shorter follow- up and Lack of measurement of Blood Levels of Glutathione.The investigators also did not estimate baseline or post- treatment renal or thyroid function of the Subjects, both of which were reported to be adversely affected by IV glutathione

The result is that the mainly oil soluble, emollient fatty alcohol is converted to an emulsifier molecule that keeps oil and water mixed in creams