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These can include: Hypersensitivity or allergic reactions Nausea, vomiting, or diarrhea Headaches or dizziness Joint pain or stiffness A flushing sensation after injection It is important to note that these risks are rare and usually mild

The escalating incidence of 25(OH)vitamin D (25(OH)VD) deficiency/inadequacy has led to increased awareness and use of vitamin D supplements by the general population and more prescriptions for vitamin D by physicians [9]

Traditional Chinese medicine has accumulated rich experience in DKD treatment, with traditional formulas and natural active monomers demonstrated to improve clinical symptoms in DKD patients through multi-target, multi-pathway holistic regulation (23)

A recent systematic review and meta-analysis highlighted the high global prevalence of diabetic foot ulceration among DPN patients, emphasizing the critical need for early detection and comprehensive management strategies to prevent severe outcomes