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In addition to hypertension, a major risk factor for cardiovascular (CV) diseases, combustible cigarettes may substantially heighten the risk of CV morbidity and mortality 5

The agency has enforcement discretion to take action and in the guidance the agency specified it could take action on any e-cigarette product that's "targeted to minors." The industry has been very creative at getting new products on the market quickly, despite regulators' efforts to curb teen use, says Cristine Delnevo, who directs the Center for Tobacco Studies at Rutgers University

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