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The distribution of data was assessed by histogram analysis, and comparisons between baseline and treatment values were conducted using two-tailed Students t-tests

doi: 10.1128/AEM.02218-06 109 PanekA.KvtekL.SmkalovM.VeeovR.KolM.RderovM.et al

doi: 10.1016/j.athoracsur.2007.05.095 65 ShankarNDalyRGeskeJKushwahaSKTimmonsMJoyceLet al

f , Left, volcano plot showing relative fold change (log 2 ) in whole cell metabolite abundance versus log 10 (P value) from KPK cells expressing a sgRNA targeting intergenic region or sgRNA targeting Slc33a1