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The enzyme is also a component of H2S signaling in cells

RNA sequencing data were deposited at NIH Gene Expression Omnibus (GEO) and are publicly available as of the date of publication at accession number GEO: GSE271623

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The expression of GPX3 was positively associated with plasma cells and M0 macrophages, whereas it exhibited a negative association with monocytes and M1 and M2 macrophages