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This distinction affects their roles: The primary neurotransmitter in the central nervous system is glutamate while glutamine serves as an essential nitrogen source for protein synthesis and other metabolic pathways

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Variants in EPAS1 and EGLN1 proteins, prevalent among Tibetan highlanders, illustrate population-specific genetic fingerprints that modulate the erythropoietic response to prolonged hypoxia and inhibit maladaptive erythrocytosis (64, 65)