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The prophylactic use of vitamin B12 was regarded as necessary for people diagnosed with atrophic gastritis, those with previous bariatric surgery, people at risk of B12 deficiency due to illnesses or medications, people with low or no consumption of animal source foods, and people ever diagnosed with vitamin B12 deficiency when they decided to become pregnant (Table 2)

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Semaglutide is often preferred for patients with milder weight-loss goals or histories of severe GI side effects, because tirzepatide tends to produce stronger nausea during titration