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We have also focused on drug repositioning studies, especially for prevention, because they should be rapidly translated to patients suffering from CIPN

It is widely recognized that these compounds exhibit significant antioxidant and anti-inflammatory properties, which alleviate the symptoms of DILI, such as cellular inflammation and cholestasis, which frequently occur in the clinic (Figure 6)

In the mitochondria, the "power plants" of the cell, a series of complex biochemical reactions take place

For this reason, more studies are needed to be able to affirm with conviction the improvements in lowmoderate-intensity performance derived from chronic supplementation protocols