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For example, binding of SCFAs to FFAR2 and GPR109A in intestinal epithelial cells stimulates K+ efflux and hyperpolarization, leading to activation of the inflammatory vesicle-activating protein NLRP3, which, in turn, induces the release of IL-18, contributing to the maintenance of integrity, repair, and intestinal homeostasis (190)

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Separate enzyme-linked immunosorbent assays (ELISAs) were used for additional inflammatory, coagulation and BBB markers and included human tissue factor (1:10 dilution, cat

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