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Analyses within individual families showed that heterozygosity for IGFALS mutations resulted in approximately 1.0 SD height loss in comparison with wild-type, whereas homozygosity or compound heterozygosity resulted in a further loss of 1.01.5 SD, suggestive of a gene-dosage effect

But if you take probiotics and prebiotics as separate supplements, you can see how your body reacts to each product and then adjust the dosage as needed