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Furthermore, it has been observed that fumarate and succinate share a similar affinity for the succinate-binding site of succinate dehydrogenase (SDH)

Neuropsychiatric abnormalities Psychiatric problems are associated with B 12 deficiency in adults between the ages of 4090 years and rarely affect people of younger age (Stanger et al., 2003)

DOI: 10.1371/journal.pone.0189051 Dickey, A.S., Sanchez, D.N., Arreola, M., Sampat, K.R., Fan, W., Arbez, N., Akimov, S., Van Kanegan, M.J., Ohnishi, K., Gilmore-Hall, S.K., Flores, A.L., Nguyen, J.M., Lomas, N., Hsu, C.L., Lo, D.C., Ross, C.A., Masliah, E., Evans, R.M., La Spada, A.R

A novel mycothiol-dependent detoxification pathway in mycobacteria involving mycothiol S-conjugate amidase