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Besides being exported via the FPN pathway, elevated expression of prominin 2 (PROM2), an intracellular iron stress response protein, can facilitates the formation of ferritin-containing multivesicular bodies (MVBs) and exosomes, which effectively reduce intracellular iron levels and prevent ferroptosis by exporting iron out of the cells (Brown et al., 2019)

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It acts as a beginning point in the methionine cycle and a precursor of S-adenosylmethionine (SAMe), a vital molecule involved in several biochemical processes