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however, geographical location and ethnicity influence the prevalence of certain symptoms Individual factors such as personal history, current health status (particularly obesity) and socioeconomic status considerably worsen a woman's experience of menopause Health-care providers should offer education to women on improving modifiable lifestyle factors to reduce the risk of future illness Menopause seems to accelerate the ageing process

517 However, PERK heterozygous deficiency exacerbates IFN-induced apoptosis of remyelinating oligodendrocytes and impairs remyelination in cuprizone-induced demyelinated lesions

doi: 10.1016/j.intimp.2023.109983 98

Trichurissuis infection alters the abundance of Proteobacteria and Deferribacteres in porcine colon microbiota [47] and increases the abundance of lactobacilli and decreases the diversity of the murine intestinal microbiota [48]