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The primary outcome was relative LF change from baseline (CFB) at 24 wks

This influx not only triggers cell contraction but also stimulates cell proliferation, up-regulates chemokines and fibroblast growth factors [72]

15 ROS include radical compounds, such as superoxide, hydroxyl radicals, and lipid hydroperoxides, and reactive nonradical compounds, such as singlet oxygen, hydrogen peroxide (H 2 O 2 ), hypochlorous acid, chloramines, and ozone