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More than half of the KEAP1 mutations that have been reported so far are distributed in the DC domain, which is essential for association with NRF2 (Taguchi et al., 2011

Relationship between anti-fungal effects and lung exposure of PC945, a novel inhaled antifungal agent, in Aspergillus fumigatus infected mice: Pulmonary PK-PD analysis of anti-fungal PC945

Recently, Chen and colleagues developed a SAD cortical organoid model from human iPSCs and exposed it to serum to mimic BBB breakage, a common AD feature, and observed increased A-like pathology, hyperphosphorylated tau, synaptic loss, and an impaired neural network [191]