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Abstract Diabetic cognitive dysfunction is one of the important comorbidities and complications of diabetes, which is mainly manifested by loss of learning ability and memory, behavioural disorders, and may even develop into dementia

During these early metabolic changes there are also increases in free radical production by the mitochondria (Step 5), which are increasingly compromised by their attempt to buffer intracellular calcium (Step 8)

The therapeutic benefit of these treatments is both inarguable and profound

Increase activity of superoxide dismutase (SOD) is shown in the A-GSH group.[16] T-BARS: T- Bars is a measurement of lipid peroxidation