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This can lead to an increase in homocysteine levels, which can inhibit the activity of methionine synthase (MS), the enzyme that converts homocysteine to methionine in the methylation cycle

Given the diverse roles of GSH in cellular physiology, the clinical significance of altered glutathione homeostasis is increasing its potential as a therapeutic agent

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In the fifteenth century, a Roman physician introduced the term oncos to describe swelling, highlighting early attempts to understand and categorize tumors