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doi: 10.3389/fimmu.2021.770402 68 KarzounBRamadanAAllababidiSFathallahAM

Basal respiration and passive proton leak across the mitochondrial membrane are increased in iPSC-derived neural cells from PINK1 PD patients, while neural cells from those with LRRK2 G2019S PD show significantly lower basal respiration relative to controls [61]