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In detail, decreased NETs formation, hepatic fibrin deposition as well as complement and coagulation factors expression were observed in NASH models following C3aR antagonist treatment

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doi: 10.1186/s12906-024-04723-8 35

Interestingly, relatively low concentrations of E2 are capable of robustly inhibiting germ cell apoptosis in cultured segments of human seminiferous tubules without survival factors (i.e., serum and hormones)