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In addition to activating endogenous T cells, the nano-STING agonist B-LNP/diABZI can enhance the migration of CAR-T cells from the circulation to GBM tumors [187]

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Engineering the MSC niche to preserve stemness Stem cells, including MSCs, maintain an undifferentiated and self-renewing state through interactions with their microenvironment, known as the stem cell niche

For instance, carnosine inhibits hyperglycemia-induced apoptosis of vascular endothelial cells and neurofibrosis, and thus delays the progression of diabetic complications (91)