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At this time, gut flora richness drops to a minimum, and resident symbiotic bacteria with protective functions (such as Lachnospiraceae and Ruminococcaceae) are largely replaced by bacteria of oral origin (such as Streptococcus and Veillonella ) and typical intestinal pathogens (such as Enterobacteriaceae), a phenomenon known as oralization

Together, bioavailability ensures effective drug absorption, while bioequivalence ensures comparable therapeutic performance between formulations

Steinbrecht S, Kammerer S, Kpper J-H (2019) HepG2 cells with recombinant cytochrome P450 enzyme overexpression: their use and limitation as in vitro liver model

A very human and respectful way to say goodbye to our loved ones