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Konopleva M, Tsao T, Ling X, Kojima K, Watt J, Mak DH, Verhaegen M, Bornmann W, Soengas M, Andreeff M

Their findings were published in an article, Paracrine Interactions within the Pancreatic Islet Determine the Glycemic Set Point, in the journal Cell Metabolism

They share the IGF-1 lineage but differ in origin, structure, receptor engagement, and duration of action, and they are not interchangeable in research