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Chan School of Public Health, (5)University of California, San Francisco, (6)Boehringer Ingelheim Pharmaceuticals, (7)Iccb-Longwood Screening Facility, Harvard Medical School, (8)Broad Institute Background: Chronic liver injury leads to hepatic stellate cell (HSC) activation and transdifferentiation into HSC myofibroblasts, which produce the extracellular matrix (ECM) responsible for fibrosis

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As shown on the right, the component colors of the visible portion can be separated by passing sunlight through a prism, which acts to bend the light in differing degrees according to wavelength

Creatine may further interface with other cellular longevity pathways, including sirtuin signaling and NAD metabolism, potentially amplifying its effects on mitochondrial health and cellular resilience [28]