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10.1016/j.femsle.2005.09.004 32 HumphriesK

Ginsenoside Rg1 downregulates calpain-1 to inhibit STAT3 phosphorylation, blocks the IL-6/STAT3 inflammatory pathway and the release of inflammatory factors, and can inhibit the activation of the TXNIP/NLRP3 inflammasome, reducing IL-1 secretion (Zhang R

Whereas the participants who took the fish oil supplement had biomarker profiles that were cardioprotective, the participants who took the placebo had biomarker profiles associated with inflammation and cardiovascular disease

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