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Common variants at 7p21 are associated with frontotemporal Lobar degeneration with TDP-43 inclusions

Additionally, in a similar fashion to what occurs in AKI, de novo NAD + biosynthesis is altered in CKD, as lower baseline levels of tryptophan and higher levels of downstream metabolites, such as quinolinate, were associated with the development of CKD in several large cohorts, including the Framingham Heart Study [158], the Cooperative Health Research in the Augsburg Region Study [159], and the Atherosclerosis Risk in Communities Study [160]

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In vivo studies of intestinal carnitine absorption in rats