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246 Sepsis often triggers a sepsis-associated encephalopathy (SAE) which presents itself with wide symptomatology including reduced attention, disrupted sleep-wakefulness balance, impaired speech and orientation, deficient leaning and memory, numerous perception disorders, focal neurological deficits, seizures, and, in terminal stages, coma

If NAC is not provided within 8 hours after APAP intoxication, plasma GST levels will keep increasing and at 4050 hours will be correlated with the time when the major liver damage occurs [48]

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