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High dose intravenous (IV) thiamine supplementation (500 mg thiamin dissolved in 100 mL normal saline) led to a reduction in the frequency of migraine attacks (20)

& Kunji, E

After intracerebral hemorrhage, the HDAC1/2 inhibitor Lomidesine (FK228) can alter microglial heterogenization, reduce neuroinflammation, and alleviate neuronal ferroptosis, possibly through regulating the Nrf2/HO-1 signaling pathway