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It was found that gastrodin could reduce blood pressure in spontaneously hypertensive rats, and its mechanism may be related to the direct reduction of Ang level or indirect inhibition of the RAAS by activating peroxisome proliferator-activated receptor (PPAR) ( Table 6 TCM preventing and treating upstream AF targets on RAAS

10.1016/j.abb.2007.04.015 Arch

They are not FDA-approved and are not for human or veterinary use.