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J Clin Invest 134:e170998

These connexons can form intercellular gap junction channels or plasmalemmal pores, known as hemichannels 470

10.1097/MD.0000000000022039 41 GiampieriF.IslamM

Neoplasia consumes glucose to generate energy through anaerobic metabolism, resulting in lactate as the final product and promoting an acidic environment that favors tumor growth