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Herein, a putative co-existence of defective DNA damage repair mechanism, together with the therapy-specific DNA damage, may explain the role of Taxol derivatives in t-SMD/t-AML that arise from cellular populations with an incredibly higher turnover (Smith, 2003)

Manganese exposure is cytotoxic and alters dopaminergic and GABAergic neurons within the basal ganglia

Following extracellular stimulationfor instance, the binding of TNF- to its cell-surface receptora cascade of intracellular signaling events is initiated

TB-500 is utilized to reinforce wound healing, decrease tissue inflammation, and minimize tissue damage