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Cobalt Allergy Potential Risks for Patients Patients with a cobalt allergy face several risks related to Vitamin B12 intake: Nutritional Deficiency : Avoiding Vitamin B12 due to allergy concerns can result in deficiency, leading to anaemia, neurological issues, and other health problems

22,23 In patients with a normal or low-normal serum vitamin B 12 level, complete blood count results demonstrating macrocytosis, or suspected clinical manifestations, a serum methylmalonic acid level is an appropriate next step 1,2,6,18 and is a more direct measure of vitamin B 12 's physiologic activity

Watch for These Signs It can be tricky to pinpoint a B12 deficiency because the symptoms often overlap with general stress or a busy lifestyle