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Concept flavors pose a challenge for enforcement of flavored tobacco restrictions, as they can make it difficult for enforcement agencies to determine whether a tobacco product meets the legal definition of a flavored tobacco product

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The presentation of negative pictures is related to activations especially in the amygdala, the ventral striatum, the insula, the anterior cingulate cortex, the medial prefrontal cortex and the orbitofrontal cortex [62,63,64]